ABPA in adulthood: a CFTR-related disorder

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ABPA in adulthood: a CFTR-related disorder.

In Western countries, allergic broncho-pulmonary aspergillosis (ABPA) in childhood is very unusual beyond the context of cystic fibrosis (CF). It is presumed to be different in adulthood, although three studies 1e3 reported an increased frequency of cystic fibrosis transmembrane conductance regulator (CFTR) mutations in adults with ABPA. Out of the 63 patients investigated in these studies, non...

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A Contraversy to Traditional Manifestation of ABPA: ABPA Without Asthma

Allergic bronchopulmonary aspergillosis (ABPA) is a complex disease triggered by hypersensitivity reaction to allergens of Aspergillus species. Aspergillus fumigatus is the most common agent of the disease. ABPA is rarely presented in the absence of asthma, which is the principle criterion for its diagnosis. In this report, we present the case of a 43-year-old man without a history of bronchial...

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A 41-year-old non-Hispanic white woman, accompanied by her psychiatrist, presented for immunologic consultation with an armload of medical records. The patient’s primary concerns were environmental mold exposure and a productive cough attributed to recurrent upper and lower respiratory tract infections. Although initially relating the beginning of her infections to mold exposure over the previo...

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ژورنال

عنوان ژورنال: Thorax

سال: 2010

ISSN: 0040-6376

DOI: 10.1136/thx.2010.145862